期刊文献+

强直性脊柱炎合并髋关节受累的临床特点 被引量:3

Clinical characteristics of ankylosing spondylitis with hip involvement
下载PDF
导出
摘要 目的探讨强直性脊柱炎(AS)伴髋关节受累的临床特征及相关因素。方法回顾分析河北医科大学第三医院住院治疗的AS患者331例,依据患者是否合并髋关节受累分为普通AS组和AS合并髋关节受累组,比较2组的一般资料、实验室指标及既往用药史,分析其危险因素。结果331例AS患者有224例(73.7%)合并有髋关节受累。AS伴髋关节受累组的年龄及发病年龄均显著低于普通AS组(P<0.01),C反应蛋白(CRP)和血小板(PLT)水平均显著高于普通AS组(P<0.05),男性比例、既往激素使用率以及发生骨质疏松的比例高于普通AS组(P<0.05)。眼炎发病率显著低于普通AS组(P<0.05)。分析显示男性(OR=4.29,P=0.007)、低龄发病(OR=2.98,P=0.003)为AS合并髋关节受累的危险因素。结论AS合并髋关节受累较常见,且合并髋关节受累者相对病情更重,更容易出现骨质疏松,男性及低龄发病为其危险因素。 Objective To evaluate the clinical characteristics and relevant factors of ankylosing spondylitis(AS)with hip involvement.Methods A total of 331 AS patients hospitalized in the Third Hospital of Hebei Medical University were divided into normal AS group and AS with hip involvement group according to if they were concurrent with hip involvement.The normal information,laboratory indicators and past medication history were compared for the risk factors between the two groups.Results Totally 244(73.7%)cases were hip involvement among 331 AS patients.Compared with normal AS group,AS with hip involvement group had decreased age at onset(P<0.01),increased levels of C-reactive protein(CRP)and platelet(PLT)(P<0.05),increased male ratio,increased past hormone use rate,increased proportion of osteoporosis(P<0.05),and decreased incidence of ophthalmitis(P<0.05).The result showed that the risk factors of AS with hip involvement were male(OR=4.29,P=0.007)and pathogenesis in low age(OR=2.98,P=0.003).Conclusion Hip involvement is more common in AS patients,and with serious illness the patients are more prone to osteoporosis.Male and early-onset are the risk factors of AS with hip involvement.
作者 李惠婷 孟景红 顾光 陈海英 王俊祥 Li Huiting;Meng Jinghong;Gu Guang;Chen Haiying;Wang Junxiang(Department of Rheumatology and Immunology, the Third Hospital of Hebei Medical University, Shijiazhuang 050051, China)
出处 《临床荟萃》 CAS 2021年第6期500-503,共4页 Clinical Focus
关键词 脊柱炎 强直性 骨关节炎 骨质疏松 眼内炎 spondylitis,ankylosing osteoarthritis,hip osteoporosis endophthalmitis
  • 相关文献

参考文献6

二级参考文献5

共引文献320

同被引文献51

引证文献3

二级引证文献6

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部