肠道菌群对高脂血症调控机制及治疗新方法研究进展

The Regulation Mechanism and New Treatment Progress of Intestinal Flora to Hyperlipidemia

高脂血症是一种由脂质代谢失调引起的疾病,能够诱发高血压、高血糖、脑卒中、心肌梗塞等心脑血管疾病。大多数对高脂血脂症的研究都是以脂肪代谢为中心展开的。目前研究发现,高脂血症患者体内肠道菌群的结构和多样性会发生改变,同时,肠道菌群紊乱亦会影响机体的脂质代谢。本文详细阐述了肠道菌群对高脂血症的调控机制,并对益生菌及益生菌发酵食品对高脂血症治疗作用进行整合分析,为发现治疗高脂血症新的靶点提供科学依据。

Hyperlipidemia is a type of disease caused by lipid metabolism disorders,which can induce hypertension,hyperglycemia,stroke,myocardial infarction and other cardiovascular diseases.Most studies of hyperlipidemia are centered on fat metabolism.Current studies have found that the structure and diversity of intestinal flora in patients with hyperlipidemia will change,and intestinal flora disorders will also affect the body’s lipid metabolism.This paper elaborates the regulation mechanism of intestinal flora on hyperlipidemia in recent years,and the probiotics and probiotics fermented food on the treatment of hyperlipidemia were integrated analysis,providing a scientific basis for finding new targets for the treatment of hyperlipidemia.