摘要
The development of functional nanocarriers with multifunctional ability and expected degradability is of great significance for efficient drug delivery on tumor therapy.The release of non-specific drugs and serious side effects severely limit their therapeutic effectiveness,although chemotherapy has been far and widely used in clinical practice[1-4].In the past few decades,nanosized drug carriers integrated with multi-responsive properties have emerged as promising candidates for anticancer treatment due to their long circulation in the bloodstream,high drug loading capacity,and“passive”targeting capability on account of the enhanced permeability and retention(EPR)effect[5-8].
