New era of stroke therapy and new challenges

The year 2015 was revolutionary for the treatment of acute ischaemic stroke(AIS)because of publication of multiple large randomised controlled clinical trials(RCTs)on the success of mechanical thrombectomy.Campbell et al provided a very comprehensive review of this topic in this issue of Stroke and Vascular Neurology.Consequently,the European and Chinese AIS guidelines have both given thrombectomy the highest level of recommendation(I,A).While we celebrate this most significant change in 20 years of stroke therapy,we also begin to contemplate what these new treatment modalities will bring.