摘要
睾丸孤核受体4(Testicular orphan nuclear receptor 4,TR4)在许多关键的生理过程中起着重要的调节作用,其控制的信号失调与许多疾病有关。近年来,TR4在前列腺癌中的作用备受关注,系统分析和认识TR4在前列腺癌的发生、发展及其治疗中的作用,对完善前列腺癌精准治疗策略具有重要意义。
Testicular orphan nuclear receptor 4(TR4)plays an important regulatory role in many key physiological processes,and the signal dysregulation it controls are related to many diseases.In recent years,the role of TR4 in prostate cancer has received increasing attention.Systematic analysis and understanding of the role of TR4 in the initiation,development,and treatment of prostate cancer are of great significance to improving the precise treatment strategy for prostate cancer.
作者
段红莉
徐东东
石宏
王绍波
DUAN Hongli;XU Dongdong;SHI Hong;WANG Shaobo(the First People’s Hospital of Yunnan Provience,PET/CT center,Kunming 650100,China;Clinical Medical College Dali University,Dali 671000;Kunming University of Science and Technology,Primate Translational Medicine Academy,Kunming 650100)
出处
《中国比较医学杂志》
CAS
北大核心
2021年第6期102-106,共5页
Chinese Journal of Comparative Medicine
基金
国家自然科学基金项目(81760306)
云南省科技厅-昆明医科大学应用基础研究联合专项(2018FE001(-291))
云南省卫生健康高层次人才(D-2018011)
关键词
前列腺癌
睾丸孤核受体4
分子靶向治疗
信号通路
分子机制
prostatic neoplasms
testicular orphan nuclear receptor 4
molecular targeted therapy
signal transduction
molecular mechanism
