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自噬在结直肠癌中的作用研究进展 被引量:9

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摘要 结直肠癌是常见的消化道肿瘤之一,早期临床症状不明显,发现时往往是中晚期。自噬是一种进化保守的正常细胞中监视机制,它通过溶酶体清除分解受损的细胞器和聚集的蛋白质,并将产生的基础营养物质重新循环利用。在结直肠癌中,自噬对肿瘤的促进与抑制双重作用广泛得到认可,因此,明确自噬对结直肠癌肿瘤细胞的作用,将为结直肠癌的治疗提供更多的理论依据。本文对自噬在结直肠癌发展过程中的作用进展进行综述。
出处 《江苏大学学报(医学版)》 CAS 2021年第4期303-306,313,共5页 Journal of Jiangsu University:Medicine Edition
基金 江苏省自然科学基金青年项目(BK20200265)。
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