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CHF患者血清NT-proANP、NT-proBNP、sST2与心功能的关系

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摘要 目的:探讨慢性心力衰竭(CHF)患者血清N-末端心房利钠肽(NT-proANP)、N-末端脑利钠肽(NT-proBNP)、可溶性基质裂解素2(sST2)与心功能的关系。方法:选取2019年6月~2020年8月期间心内科收治的120例CHF患者,根据纽约心脏病协会(NYHA)心功能分级将其划分为心功能Ⅱ级组(n=40)、Ⅲ级组(n=50)及Ⅳ级组(n=30),另选取同期体检正常的50例为对照组。检测研究对象血清中NT-proANP、NT-proBNP、sST2表达情况,并比较分析各组研究对象的一般资料与实验检测结果。结果:与对照组相比,心功能Ⅱ级组、Ⅲ级组及Ⅳ级组NT-proANP、NT-proBNP、sST2水平均更低(P<0.05)。经相关性分析发现,患者血清NT-proANP、NT-proBNP、sST2表达水平与心功能分级呈正相关(P<0.05)。结论:CHF患者的血清NT-proANP、NT-proBNP、sST2表达水平随着心功能分级的严重程度而上升,临床可将其作为诊断CHF及评价心功能的客观依据。
作者 梁牧
出处 《医学食疗与健康》 2021年第10期149-150,共2页 Medical Diet and Health
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