初乳口腔免疫疗法在NICU早产儿中的应用效果

Application effects of colostrum oral immune therapy on premature infants in NICU

目的:观察初乳口腔免疫疗法在NICU早产儿中的应用效果。方法:选取76例NICU早产儿为研究对象,按照随机数字表法分为对照组与观察组各38例,对照组给予常规护理,观察组在对照组基础上给予初乳口腔免疫疗法。比较两组经口喂养时间、喂养不耐受事件发生率和护理前后发育指标水平。结果:观察组开始经口喂养时间和完全经口喂养时间均短于对照组,差异有统计学意义(P<0.05);观察组喂养不耐受事件发生率为13.16%,低于对照组的34.21%,差异有统计学意义(P<0.05);护理后,两组体质量、头围和身长均高于护理前,且观察组高于对照组,差异有统计学意义(P<0.05)。结论:在常规护理基础上对NICU早产儿实施初乳口腔免疫疗法,可提高发育指标水平,缩短经口喂养时间,降低喂养不耐受事件发生率,优于单纯常规护理效果。

Objective:To study application effects of colostrum oral immune therapy on premature infants in NICU.Methods:76 premature infants in NICU were selected as the research objects,and were divided into control group and observation group according to the random number table method,38 cases in each group.The control group was given routine nursing,while the observation group was given colostrum oral immune therapy on the basis of that of the control group.The oral feeding time,the incidence of feeding intolerance events and the levels of development indicators before and after the nursing were compared between the two groups.Results:The oral feeding start time and the complete oral feeding time of the observation group were shorter than those of the control group,and the differences were statistically significant(P<0.05).Further,the incidence of feeding intolerance events in the observation group was 13.16%,which was lower than 34.21%in the control group,and the difference was statistically significant(P<0.05).After the nursing,the body weight,the head circumference and the body length of the two groups were higher than those before the nursing;those of the observation group were higher than those of the control group;and the differences were statistically significant(P<0.05).Conclusions:On the basis of the routine nursing,the colostrum oral immune therapy for the premature infants in NICU can improve the levels of development indicators,shorten the oral feeding time,and reduce the incidence of feeding intolerance events.Moreover,it is superior to single routine nursing.