摘要
Objective The objectives of this study were to estimate influenza vaccination coverage among patients with diabetes mellitus in an Italian 250000-inhabitant area in the 2017-2018 season and to assess whether glycaemic control and pharmacological treatment were associated with the likelihood of being vaccinated.Design In this cross-sectional study,we analysed anonymous health administrative databases,linked with each other at the individual patient level through a stochastic key:diabetes mellitus registry,vaccinations,drug prescriptions and laboratory database.setting The study was conducted in the catchment area of the University Hospital of Udine(‘the Udine area’),a 250000-inhabitant area in the northeast of Italy.Participants The study included all subjects included in the regional registry of patients with diabetes mellitus,living in the Udine area as of 1 October 2017.Main outcome measures Vaccination coverage in the 2017-2018 influenza season was calculated.The association between patients’characteristics and the likelihood of being vaccinated was assessed through multivariate log binomial regression.result 53.0%of 15900 patients with diabetes living in the area were vaccinated.Coverage increased with age,approaching 75%at≥85 years.Patients lacking recent glycated haemoglobin testing were less likely to be vaccinated(43.4%vaccination coverage),as were those not treated pharmacologically(44.4%vaccination coverage).Patients treated with both insulin,metformin and other antidiabetic medications were more likely to be vaccinated than those treated with metformin alone(58.1%vaccination coverage;adjusted relative risk=1.07,95%CI 1.01 to 1.14).Conclusion Influenza vaccination coverage was suboptimal in this Italian population of patients with diabetes.Strategies to improve diabetes management could in turn positively affect influenza coverage.
