摘要
American trypanosomiasis,commonly known as Chagas disease,is caused by the flagellate protozoan parasite Trypanosoma cruzi.An estimated eight million people infected with T.cruzi currently reside in the endemic regions of Latin America.However,as the disease has now been imported into many non-endemic countries outside of Latin America,it has become a global health issue.We reviewed the transmission patterns and current status of disease spread pertaining to American trypanosomiasis at the global level,as well as recent advances in research.Based on an analysis of the gaps in American trypanosomiasis control,we put forward future research priorities that must be implemented to stop the global spread of the disease.
基金
This work was supported by the National S&T Major Programme(grant no.2012ZX10004220)
Many thanks for Dr.Peiling Yap for her constructive comments on the manuscript.Many thanks also to Mr.Xue Jingbo and Mr.Shen Haimo for their help in drawing the figures.
