摘要
目的对比常规液体复苏和限制性液体复苏抢救创伤失血性休克患者的效果。方法2017年1月至2020年4月,对本院急诊外科采集的40例创伤失血性休克患者的资料进行分析,按照投掷硬币法将其分为对照组和观察组,比较两组患者的死亡率、并发症及炎症介质水平。结果与对照组相比,观察组的死亡率、并发症的总发生率、输液量、血乳酸、凝血酶原时间、炎性介质水平均明显降低(P<0.05),血氧饱和度明显增加(P<0.05)。结论与常规液体复苏相比,限制性液体复苏能够更好地减少输液量,降低血乳酸及炎症介质水平,缩短凝血酶原时间,提高血氧饱和度,降低并发症及死亡率。
Objective To compare the efficiency of conventional fluid resuscitation and restrictive fluid resuscitation for the treatment of patients with trauma hemorrhagic shock.Methods 40 patients with traumatic hemorrhagic shock enrolled from the emergency surgery department of our hospital from January 2017 to April 2020.All of them are divided into two groups randomly,namely control group and experimental group.Then the mortality,complication,laboratory tests and inflammatory mediator level were compared between the two group.Results The mortality,complication incidence,infusion volume,blood lactate,prothrombin time and inflammatory mediator level(P<0.05)was significant decreased while oxygen saturation(P<0.05)was markedly in experimental group compared with that of control group.Conclusions Compared with conventional fluid resuscitation,restrictive fluid resuscitation can better reduce the volume of fluid administered,decrease the levels of blood lactate and inflammatory mediators,shorten the prothrombin time,improve oxygen saturation,and reduce complications and mortality.
作者
李秀兵
邓华余
姚狮章
姚砚灿
邓文福
Li Xiubing;Deng Huayu;Yao Shizhang;Yao Yancan;Deng Wenfu(De-partment of emergency surgery,the fourth people's Hospital of south China sea region,Foshan,China.)
关键词
液体复苏
失血性休克
炎症介质
死亡率
Fluid resuscitation
Hemorrhagic shock
Inflammatory mediators
Mortality