四川省新型冠状病毒肺炎无症状感染者及其转归情况分析

Analysis of Asymptomatic COVID-19 Infections and Conversion to Diagnose in Sichuan Province

目的了解四川省新型冠状病毒肺炎无症状感染者的流行病学特征及转归情况,为新冠肺炎防控提供科学依据。方法采用回顾性分析的方法,描述四川省2020-01/03新冠肺炎无症状感染者的人口学特征、时间分布,分析无症状感染者的转归情况,比较无症状感染者转为确诊病例与其他确诊病例在人口学特征、临床严重程度以及病程上的异同。结果160例无症状感染者主要通过对密切接触者主动检测、重点人群筛查以及入境人员主动检测等方式发现。其年龄、职业分布广泛,男女性别比接近1∶1;有70例随后出现临床症状转为确诊病例,时间间隔中位数为2 d;不同年龄段转为确诊的比例不同。与其他确诊病例相比,无症状感染者转为确诊病例的重症和危重症比例较低,病程较短。结论四川省通过主动检测有效的发现了大量无症状感染者,并及时对无症状感染者及时进行管理,有效控制了其作为传染源传播病毒,对四川省疫情防控起到了积极作用。

Objective To understand the epidemiological characteristics and prognosis of asymptomatic COVID-19 infections in Sichuan province,so as to provide scientific basis for the prevention and control of COVID-19.Methods Retrospective analysis was used to describe the demographic characteristics and time distribution of asymptomatic COVID-19 infected persons in Sichuan province,and to analyze the transition from asymptomatic infected persons to confirmed cases,and the differences in demographic characteristics,clinical severity and course of disease between confirmed cases from asymptomatic infected persons and other confirmed cases were compared.Results The160 cases of asymptomatic infected persons were mainly detected through active detection of close contacts,screening for key population,and active detection of persons from abroad.Its age,occupation distribution was widespreading,the ratio of male to female was close to 1∶1.There were 70 cases showing clinical symptoms soon afterwards and the median interval was 2 days.The rate of conversion to confirmed cases was different by age group.Compared with other confirmed cases,the proportion of severe and critical cases in confirmed cases from asymptomatic infected persons was lower and the course of illness was shorter.Conclusion A large number of asymptomatic infected persons were found through active testing in Sichuan province.Timely management of asymptomatic infected persons effectively controlled the spread of the virus as a source of infection,and it played a positive role in the prevention and control of the epidemic in Sichuan province.