一起鼠伤寒沙门菌单相变异株引起食源性疾病暴发的检测分析

A Food-borne Disease Outbreak Caused by Monophasic Variant of Salmonella Typhimurium

目的对1起农村家宴所致疑似细菌性食源性疾病暴发进行病原学检验与溯源分析,为患者诊治、事件处置提供依据。方法 2019-05广元市某县发生1起村民家中自办丧宴所致食源性疾病暴发事件,根据流行病学调查信息,采集患者粪便或肛拭和可疑食物,开展病原菌分离鉴定、药敏试验、脉冲场电泳(PFGE)试验、分子分型聚类与溯源分析。结果从3例患者粪便标本和4份可疑食品中均检出鼠伤寒沙门菌单相变异株;PFGE聚类分析结果显示患者分离株与食品分离株PFGE型别一致;所有分离株均对氨苄西林、四环素、氯霉素、复方新诺明耐药。结论本次食源性疾病由鼠伤寒沙门菌单相变异株污染食品所致。

Objective To analyze a suspected bacterial foodborne disease outbreak caused by a family feast in rural areas in order to provide a basis for patient diagnosis and treatment as well as event management. Methods A foodborne disease outbreak occurred in a county in Guangyuan City in May2019 caused by a villager′s funeral banquet. Epidemiological investigation was performed. Samples of feces or anal swabs,and suspicious food were collected. Pathogen isolation and identification,drug sensitivity test, pulse field electrophoresis(PFGE) test, molecular typing cluster and traceability analysis were conducted. Results The monophasic variants of Salmonella Typhimurium was detected from stool samples of 3 patients and 4 suspicious food samples. PFGE cluster analysis showed that the PFGE type of the patient isolates was consistent with that of the food isolates. All isolates were resistant to ampicillin, tetracycline,chloramphenicol and cotrimoxazole. Conclusion This foodborne illness was caused by the contamination of food by the monophasic variant of Salmonella typhimurium.