主动终止妊娠人群生殖道沙眼衣原体感染流行情况及影响因素

Prevalence and influencing factors of Chlamydia trachomatis in China women undergoing termination of pregnancy

目的本研究旨在评估深圳市主动终止妊娠人群沙眼衣原体(CT)感染的患病率,并探讨其危险因素。方法通过问卷调查的方式收集了在宝安区公立医院妇产科门诊主动寻求终止妊娠的患者(14~51岁)的基本信息,采用聚合酶链式反应荧光探针法对自我采集尿液样本中CT和淋球菌(NG)进行核酸检测。结果在1553名研究对象中,CT感染率为10.56%(95%CI:9.03%~12.09%),NG感染率为0.45%(95%CI:0.12%~0.78%),CT/NG共感染率为0.13%(95%CI:0.050%~0.31%)。通过Logistics回归分析发现,低年龄(<20岁)(aOR=2.98,95%CI:1.21~7.33,P=0.017)、离异(aOR=2.00,95%CI:1.01~3.97,P=0.049)均为CT感染的独立危险因素。结论主动终止妊娠人群CT感染率较高,在该人群采用主动筛查和有效治疗的策略具有重大的公共卫生学意义。

Objective To understand the prevalence rate and its risk factors of Chlamydia(CT)infection among women requesting termination of pregnancy(TOP)in Shenzhen.Methods We collected basic information about the patients(14-51 years)who sought TOP in the obstetrics and gynecology clinic of Baoan District public hospital through a questionnaire survey.CT and Neisseria gonorrhoeae(NG)infection was determined by Polymerase Chain Reaction(PCR)fluorescent probe method on self-collected urine specimens.Results Of 1,553 participants recruited,10.56%(95%CI:9.03%-12.09%)tested positive for CT,0.45%(95%CI:0.12%-0.78%)tested positive for NG,and 0.13%(95%CI:0.050%-0.31%)tested positive for CT/NG co-infection.According to logistics regression analysis,it was found that low age(<20 years old)(aOR=2.98,95%CI:1.21-7.33,P=0.017)and divorced(aOR=2.00,95%CI:1.01-3.97,P=0.049)were independent risk factors for CT infection.Conclusion CT infection rate is high in women attending TOP,and it is of great public health significance to adopt a screen-and-treat strategy in this population.