栓塞微粒球联合CT引导下射频消融治疗肝癌的疗效观察

Efficacy of embolization microsphere combined with CT-guided radiofrequency ablation in treatment of liver cancer

目的探讨肝癌患者采用栓塞微粒球联合CT引导下射频消融治疗的临床疗效。方法选取2014年1月至2019年12月间黄梅县人民医院收治的200例肝癌患者,采用随机数表法分为观察组和对照组,每组100例。观察组患者采用栓塞微粒球联合CT引导下射频消融治疗,对照组患者采用栓塞微粒球治疗,比较两组患者诊疗前后的肝功能改善情况和诊疗疗效。结果诊疗后,观察组患者谷丙转氨酶、谷草转氨酶、甲胎蛋白和总胆红素均低于对照组,差异均有统计学意义(均P<0.05)。观察组患者总有效率为85.0%,高于对照组的73.0%,差异有统计学意义(P<0.05)。结论栓塞微粒球联合CT引导下射频消融治疗肝癌患者,可减少肿瘤体积,缓解恶心呕吐等临床症状,提升临床疗效,值得临床推广应用。

Objective To discuss the clinical efficacy of embolization microsphere combined with CT guided radiofrequency ablation in treatment of liver cancer. Methods Two hundred patients with liver cancer admitted to Huangmei County People’s Hospital from January 2014 to December 2019 were selected.They were randomly categorized into an observation group and control group with 100 patients in each group.The observation group received embolized microsphere combined with CT guided radiofrequency ablation and the control group received embolized microsphere. The improvement in liver function and curative effect were compared between the two groups before and after treatment. Results After the treatment,alanine aminotransferase,aspartate aminotransferase,fetoprotein and total bilirubin levels were lower in the observation group than in the control group( all P<0.05). The overall efficacy rate was 85. 0% in the observation group which was higher than was 73. 0% of the control group( P<0.05). Conclusion Embolization microsphere combined with CT-guided radiofrequency ablation in treatment of liver cancer can help to control the progress of disease,reduce tumor volume,relieve nausea and vomiting and other clinical symptoms,and improve the clinical efficacy. Thus it is worthy of promotion in clinical practice.