百色地区胆石症影响因素的调查研究

Investigation of the influencing factors on the gallstone disease in Baise area

目的探究百色地区胆石症(GD)发生的影响因素,为本地区GD的防治提供参考。方法选取右江民族医学院附属医院2019年8月1日—12月31日期间在肝胆外科接受治疗的153例GD患者作为病例组,同时选取138例同期在我院健康体检的人群作为对照组。自制调查问卷,调查两组研究对象的一般资料、健康史及生活习惯,测定两组的总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)水平,通过单因素分析和二元Logistic回归分析探究GD发生的相关因素。结果单因素分析显示病例组女性例数、年龄、BMI、合并糖尿病、高脂血症、喜饮茶(每周>3次)、饮用山泉水及血脂指标TC、TG水平高于对照组,差异有统计学意义(P<0.05),两组在合并脂肪肝、久坐及HDL-C、LDL-C水平的比较上差异无统计学意义(P>0.05)。二元Logistic回归分析显示年龄(OR=1.04,P<0.001)、BMI(OR=1.16,P=0.047)、TC(OR=2.94,P=0.009)、TG(OR=2.98,P=0.001)、合并糖尿病(OR=4.91,P=0.015)及饮用山泉水(OR=7.91,P<0.001)与GD的发生密切相关。结论年龄、BMI、TC、TG、合并糖尿病及饮用山泉水是本地区GD发生的影响因素。

Objective To explore the influencing factors on the occurance of gallstone disease(GD)in Baise area,so as to provide reference for the prevention and treatment of GD in this area.Methods For the case group,we selected a total of 153 patients with GD treated in the Department of Hepatobiliary Surgery in the Affiliated Hospital of Youjiang Medical University for Nationalities from August 1,2019 to December 31,2019.At the same time,138 people whose physical examination results in our hospital indicated healthy during the same period were selected as the control group.A self-made questionnaire was conducted to investigate the general information,health history and living habits of these two groups.We tested the levels of their total cholesterol(TC),triglyceride(TG),high-density lipoprotein cholesterol(HDL-C)and low-density lipoprotein cholesterol(LDL-C).Univariate analysis and binary logistic regression analysis were carried out to explore the related factors on the GD.Results Univariate analysis showed that the number of female cases,ages of patients,BMI,cases with diabetes mellitus,hyperlipidemia,cases who liked drinking tea(>3 times a week)and mountain spring water,TC and TG levels in the case group were higher than those in the control group,with statistical significance(P<0.05).Binary Logistic regression analysis revealed that factors including age(OR=1.04,P<0.001),BMI(OR=1.16,P=0.047),TC(OR=2.94,P=0.009),TG(OR=2.98,P=0.001),diabetes mellitus(OR=4.91,P=0.015)and drinking mountain spring water(OR=7.91,P<0.001)were closely related to the occurrence of GD.Conclusion Age,BMI,TC,TG,diabetes mellitus and drinking mountain spring water are the influencing factors on the occurance of GD in this area.