摘要
胃癌是我国最常见的一种恶性肿瘤,其中进展期胃癌(advanced gastric cancer,AGC)占80%。新辅助化疗(neoadjuvant Chemotherapy,NAC)在AGC的治疗中起着非常重要的作用。NAC可显著缓解进展期胃癌的的进展,提高AGC的R0根治率,改善患者的临床结局。目前进展期胃癌的NAC周期尚不统一,手术时机的选择也各不相同。本文回顾了进展期胃癌NAC周期和手术时机的研究进展,以期帮助医生控制化疗周期,选择手术时机。
Gastric cancer,including 80%of advanced gastric cancer(AGC),is one of the most common malignant tumors in China.Neoadjuvant chemotherapy plays an important role in the treatment of AGC.Neoadjuvant chemotherapy can significantly alleviate the progress of AGC,increase R0 resection rate,and improve the clinical outcome of AGC patients.However,choices neoadjuvant chemotherapy cycles and surgical timing vary.This paper reviews progress in research on neoadjuvant chemotherapy cycles and surgical timing for AGC,which aims to help doctors select chemotherapy cycles and surgical timing for AGC patients.
作者
张树泽
李凡
杨含腾
焦作义
Zhang Shuze;Li Fan;Yang Hanteng;Jiao Zuoyi(Department of General Surgery,Lanzhou University Second Hospital,Lanzhou 730030,Gansu,China)
出处
《肿瘤预防与治疗》
2021年第6期581-586,共6页
Journal of Cancer Control And Treatment
基金
甘肃省高等学校创新基金项目(编号:2020 B-046)
兰州市城关区人才创新创业项目(编号:2020-2-11-8)
兰州大学第二医院“萃英科技创新”计划项目(编号:CY2019-BJ03)。
关键词
进展期胃癌
新辅助化疗
化疗周期
手术时机
Advanced gastric cancer
Neoadjuvant chemotherapy
Chemotherapy cycle
Surgical timing
