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心理干预对晚期前列腺癌药物去势治疗患者情绪和生活质量影响的研究 被引量:5

Effect of psychological intervention on moods and quality of life of patients with advanced prostatic carcinoma receiving androgen deprivation therapy
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摘要 目的分析心理干预对晚期前列腺癌药物去势治疗患者情绪和生活质量的影响。方法选取2018年1月—2020年12月于空军第九八六医院泌尿外科诊治的86例晚期前列腺癌患者,按照数字随机表法均分为对照组(行传统护理)和研究组(在传统护理基础上行心理疏导),各43例。分别于药物去势治疗前、治疗后3、6个月,评价2组患者焦虑自评量表(SAS)、抑郁自评量表(SDS)、欧洲癌症研究和治疗协作组生活质量核心问卷(QLQ-C30)的评分情况。结果治疗前,2组的SAS、SDS以及QLQ-C30评分差异无统计学意义(P>0.05),治疗后3、6个月,研究组SAS和SDS评分均低于治疗前(P<0.05),且低于对照组(P<0.05)。治疗后3个月,对照组QLQ-C30评分与术前比较,差异无统计学意义(P>0.05)。治疗后3、6个月,研究组QLQ-C30中的情感功能、角色功能、认知功能、整体生活质量评分均高于治疗前(P<0.05);治疗后6个月,研究组躯体功能评分高于治疗前(P<0.05)。治疗后3、6个月,研究组情感功能、角色功能、认知功能、整体生活质量评分较对照组均显著提高(P<0.05)。结论心理干预可有效缓解晚期前列腺癌患者药物去势治疗后的不良情绪,提升生活质量。 Objective To evaluate the effect of psychological intervention on levels of anxiety and depression and quality of life of patients with advanced prostatic carcinoma prostate cancer under androgen deprivation therapy.Methods Between January 2018 and December 2020,86 patients with advanced prostate cancer treated in the Department of Urology were selected and equally divided into the control group(traditional nursing)and the study group(psychological counseling plus traditional nursing)using the random number table method.The scores of self-rating anxiety scale(SAS),self-rating depression scale(SDS),and scores of quality of life core questionnaire(QLQ-C30)by the European Organization for Cancer Research and Treatment were evaluated before treatment,3 months and 6 months after treatment.Results Before treatment,the SAS,SDS and QLQ-C30 scores were not significantly different between the study group and control group(P>0.05).At 3 months and 6 months after treatment,SAS and SDS scores in the study group became lower(P<0.05),and were significantly lower than those of the control group(P<0.05).At 3 months after treatment,the QLQ-C30 score in the control group did not change significantly(P>0.05).At 3 months and 6 months after treatment,the scores of emotional function,role function,cognitive function and overall quality of life in the study group became higher(P<0.05).At 6 months after treatment,the score of body function in the study group was higher(P<0.05).At 3 months and 6 months after treatment,the scores of emotional function,role function,cognitive function and overall quality of life in the study group were significantly higher than those of the control group(P<0.05).Conclusion Psychological intervention after androgen deprivation therapy can effectively boost patients'mood and improve their quality of life.
作者 杜丽娜 赵柯 张武合 魏英娟 苏燕胜 DU Lina;ZHAO Ke;ZHANG Wuhe;WEI Yingjuan;SU Yansheng(Department of Urology,The 986 hospital of The PLA Air Force,Xi′an 710054,China;不详)
出处 《空军医学杂志》 2021年第2期152-155,共4页 Medical Journal of Air Force
关键词 晚期前列腺癌 药物去势治疗 心理干预 焦虑 抑郁 生活质量 advanced prostatic carcinoma androgen deprivation therapy psychological nursing anxiety depression quality of life
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