加味温胆汤辅治心肌梗死PCI后56例临床观察

Clinical observation of the effect of modified Wendan Decoction in adjuvant therapy for patients with myocardial infarction after PCI:56 cases

目的观察加味温胆汤辅治心肌梗死PCI后的疗效及对患者炎症反应和睡眠质量的影响。方法112例心肌梗死PCI患者随机分为对照组(常规西药治疗)和研究组(常规西药联合加味温胆汤治疗),每组56例,均治疗2个月,观察两组患者用药前后炎症因子、心功能变化及睡眠质量的差异。结果治疗后,两组患者的TNF-α、hs-CRP、IL-6水平均较治疗前下降,LVEDD较治疗前缩短,且以研究组更为显著(P<0.05);研究组患者的睡眠质量明显优于对照组(P<0.05)。结论加味温胆汤可有效降低PCI后患者炎症因子水平,改善患者的心功能及睡眠质量。

Objective To observe explore the effect of modified Wendan Decoction in adjuvant therapy for patients with myocardial infarction after PCI and its impact on the inflammatory response and sleep quality of patients.Methods A total of 112 cases of patients with myocardial infarction after PCI were divided into the Control Group(routine treatment with western medicine)and Study Group(treatment with western medicine combined with modified Wendan Decoction)according to random number method,56 cases in each group.Both groups received the treatment for 2 months.The differences in the inflammatory factors,cardiac function changes and sleep quality before and after medication were compared between the two groups.Results After the treatment,both groups had the TNF-α,hs-CRP and IL-6 level significantly decreased compared with those before the treatment,and had the LVEDD shortened compared with that before the treatment,and the Study Group showed a more significant change(P<0.05).The Study Group had the sleep quality superior to that of the Control Group(P<0.05).Conclusion Modified Wendan Decoction can effectively reduce the level of inflammatory factors and improve cardiac function and sleep quality in patients after PCI.