欣母沛治疗宫缩乏力性产后出血的临床研究

Clinical study of hemabate in the treatment of postpartum hemorrhage caused by uterine inertia

目的探讨针对宫缩乏力性产后出血患者应用欣母沛的治疗效果。方法选取本院2019年1月至2020年1月收治的96例宫缩乏力性产后出血患者作为观察对象,在常规治疗的基础上,对照组(n=48)应用米索前列醇;观察组(n=48)应用欣母沛,比较两组治疗效果。结果观察组止血有效率为97.92%(47/48),显著高于对照组的79.17%(38/48);治疗后2h、24h,观察组的出血量明显少于对照组;观察组用药不良反应发生率为6.25%(3/48),显著低于对照组的35.42%(17/48),差异具有统计学意义(P<0.05)。结论针对宫缩乏力性产后出血患者的治疗,欣母沛止血效果好、安全性高。

Objective:To investigate the effect of hemabate on postpartum hemorrhage caused by uterine inertia.Methods:96 cases of postpartum hemorrhage due to uterine atony in our hospital from January 2019 to January 2020 were selected as the observation objects.On the basis of conventional treatment,the control group(n=48)took misoprostol;the observation group(n=48)applied hemabate,and the treatment effect of the two groups was compared.Results:The hemostatic effective rate of the observation group was 97.92%(47/48),which was significantly higher than 79.17%(38/48)of the control group;the bleeding volume of the observation group was significantly less than that of the control group at 2h and 24h after treatment;the incidence of adverse drug reactions in the observation group was 6.25%(3/48),which was significantly lower than 35.42%(17/48)of the control group,the difference was statistically significant(P<0.05).Conclusion:Hemabate has good hemostatic effect and high safety in the treatment of postpartum hemorrhage caused by uterine inertia.