双波长PDL/Nd:YAG激光治疗增生性瘢痕的有效性及安全性

Effectiveness and safety of dual-wavelength PDL/Nd:YAG laser in the treatment of hyperplastic scar

目的探究分析双波长PDL/Nd:YAG激光治疗增生性瘢痕的有效性及安全性。方法选择2019年1月至2020年1月在我院就诊的64例增生性瘢痕患者作为研究对象,根据其治疗方案不同分为对照组和观察组,对照组(n=32)采用脉冲染料激光治疗,观察组(n=32)采用双波长PDL/Nd:YAG激光进行治疗,比较两组治疗总有效率、治疗前后患者瘢痕评估量表(PSAS)和观察者瘢痕评估量表(OSAS)评分变化、治疗相关不良反应发生率以及患者满意度。结果两组治疗总有效率比较差异无统计学意义(P>0.05)。治疗后,两组的PSAS、OSAS评分均较治疗前显著降低,且观察组明显低于对照组(P<0.05)。观察组不良反应发生率3.13%,显著低于对照组18.75%(P<0.05)。随访6个月,观察组病人对治疗效果的满意度显著高于对照组(P<0.05)。结论双波长PDL/Nd:YAG激光治疗增生性瘢痕能够获得良好效果,显著改善患者的瘢痕状态,且不良反应发生率低,患者接受度高,值得推广。

Objective To explore the efficacy and safety of dual-wavelength PDL/Nd:YAG laser in the treatment of hyperplastic scar.Methods 64 cases of patients with hyperplastic scar treated in our hospital from January 2019 to January 2020 were selected as the research objects.They were divided into control group and observation group according to different treatment schemes.The control group(n=32)was treated with pulsed dye laser,and the observation group(n=32)was treated with dual-wavelength PDL/Nd:YAG laser.The total response rate,changes in patient scar assessment scale(PSAS)and observer scar assessment scale(OSAS)scores before and after treatment,incidence of treatment-related adverse reactions and patient satisfaction were compared between the two groups.Results There was no significant difference in the total effective rate between the two groups(P>0.05).After treatment,PSAS and OSAS scores in two groups were significantly lower than before treatment,and the observation group were significantly lower than control group(P<0.05).The incidence of ADR in observation group was 3.13%,significantly lower than 18.75%in control group(P<0.05).After 6 months of follow-up,the satisfaction of observation group was significantly higher than control group(P<0.05).Conclusion Dual wavelength PDL/Nd:YAG laser treatment of hyperplastic scar can achieve good results,significantly improve the scar status of patients,and the incidence of adverse reactions is low,the patient acceptance is high,worthy of promotion.