强化胰岛素泵治疗糖尿病合并重症肺部感染的临床效果

Clinical Effect of Intensified Insulin Pump in the Treatment of Diabetes Complicated with Severe Pulmonary Infection

目的探析糖尿病合并重症肺部感染患者接受强化胰岛素泵治疗的临床效果。方法于2019年1月—2021年1月选取医院接收的92例糖尿病合并重症肺部感染患者,应用统计学单盲分组方式将其分为参照组与观察组,每组46例,参照组患者用药方式为常规胰岛素治疗,观察组患者应用强化胰岛素泵方式施以治疗,比较两组患者临床治疗效果、炎症因子水平以及血糖水平的变化。结果观察组患者的临床治疗效果为93.5%,高于参照组,差异有统计学意义(P<0.05);观察组肿瘤坏死因子-α(TNF-α)为(29.47±3.04)ng/L、白细胞介素-8(IL-8)为(21.35±3.17)pg/mL、白细胞介素-6(IL-6)为(28.94±3.68)pg/mL,空腹血糖(FPG)为(6.28±1.07)mmol/L、餐后2 h血糖(2 hPG)(8.55±1.28)mmol/L、血糖达标时间为(7.01±2.11)d,优于参照组,差异有统计学意义(t=11.323、5.958、11.090、3.644、7.258、7.861,P<0.05)。结论糖尿病合并重症肺部感染患者应用强化胰岛素泵治疗,其炎症因子水平得到显著改善,患者血糖水平得到有效控制,可提升患者临床治疗效果,对于患者的预后具有积极意义,可在临床上推广。

Objective To analyze the clinical effect of intensive insulin pump therapy in patients with diabetes mellitus complicated with severe pulmonary infection.Methods From January 2019 to January 2021,92 diabetic patients with severe pulmonary infection were selected from the hospital,and they were divided into the reference group and the observation group using statistical single-blind grouping,each with 46 cases.The medication mode of the patients in the reference group was conventional insulin therapy.The observation group applied an intensified insulin pump method to treat the patients,and compared the clinical treatment effects,inflammatory factor levels and blood glucose levels of the two groups of patients.Results The clinical treatment effect of the observation group was 93.5%,which was higher than that of the reference group,the difference was statistically significant(P<0.05);the observation group TNF-αwas(29.47±3.04)ng/L,IL-8 was(21.35±3.17)pg/mL,IL-6 was(28.94±3.68)pg/mL,FPG was(6.28±1.07)mmol/L,2 hPG was(8.55±1.28)mmol/L,blood glucose compliance time was(7.01±2.11)d,which were better than the reference group,the difference was statistically significant(t=11.323,5.958,11.090,3.644,7.258,7.861,P<0.05).Conclusion Intensified insulin pump therapy for patients with diabetes complicated with severe lung infection can significantly improve the level of inflammatory factors and effectively control the blood glucose level of the patient.This can improve the clinical treatment effect of the patient and has positive significance for the prognosis of the patient.It can be promoted in the clinic.