男男性行为人群HIV暴露后预防服务的使用意愿调查

Willingness of post-exposure prophylaxis and possible related factors in men who have sex with men

目的分析MSM对HIV暴露后预防(PEP)服务的使用意愿及其相关因素。方法采用横断面调查方法,2019年9-11月通过“i卫士”微信公众号招募年龄≥18岁、最近6个月发生同性肛交或口交的男性为研究对象。结果研究对象MSM共1517人,听说过PEP服务的研究对象占72.5%(1100/1517),PEP服务的使用意愿为87.9%(1333/1517)。多因素logistic分析结果显示,更愿意使用PEP服务的因素包括年龄>25岁(OR=1.807,95%CI:1.090~2.995)、曾经做过HIV检测(OR=1.953,95%CI:1.171~3.256)、至少了解1条PEP知识(OR=2.163,95%CI:1.468~3.186);不了解性伴HIV感染状况者(OR=0.602,95%CI:0.407~0.890)的PEP服务的使用意愿较低。在听说过PEP服务的MSM中,更愿意使用PEP服务的因素包括居住地为浙江省(OR=1.942,95%CI:1.097~3.438)、年龄>25岁(OR=2.431,95%CI:1.331~4.439)、至少了解1条PEP知识(OR=3.714,95%CI:1.532~9.007)、通过MSM社区组织/志愿者/卫生专业机构了解PEP服务(OR=1.902,95%CI:1.096~3.301)。结论MSM对PEP服务的使用意愿较高,年龄、PEP知识、是否了解性伴HIV感染状况是其相关因素。MSM社区组织、志愿者及卫生专业机构是开展PEP服务宣传和推广的重要途径。

Objective To analyze the willingness of post-exposure prophylaxis(PEP)to prevent HIV transmission and related factors in men who have sex with men(MSM).Methods Cross sectional survey design was used in this study.After informed consent,MSM aged 18 years or above and having had homosexual anal or oral sex in the past 6 months were recruited through"i WeChat"official account between September and November,2019.Results Of 1517 MSM were surveyed,the proportion of MSM who had ever heard of PEP were 72.5%(1100/1517)and 87.9%(1333/1517)of the MSM said they would like to use PEP if it is needed.Multivariate logistic regression analysis suggested that aged above 25 year(OR=1.807,95%CI:1.090-2.995),HIV test history(OR=1.953,95%CI:1.171-3.256)and being aware of PEP(OR=2.163,95%CI:1.468-3.186)were the positive factors for PEP use,but an aware of the HIV status of sexual partner was the negative factor for PEP(OR=0.602,95%CI:0.407-0.890).Among MSM who had ever heard of PEP,the positive factors for PEP use included living in Zhejiang(OR=1.942,95%CI:1.097-3.438),aged above 25 years(OR=2.431,95%CI:1.331-4.439),being aware of PEP(OR=3.714,95%CI:1.532-9.007)obtaining information about PEP service from MSM organization/volunteer/health organization.Conclusions MSM's willingness to use PEP services was relatively high.Age,awareness of PEP related knowledge,and awareness of sexual partner's HIV infection status were the related factors.MSM organization/volunteer/health organization were the main forces for PEP promotion in MSM.