期刊文献+

T细胞与肿瘤细胞共培养方法及其应用进展 被引量:1

原文传递
导出
摘要 T细胞作为主要的免疫细胞在肿瘤发展和治疗的各个阶段发挥重要作用,而T细胞与肿瘤细胞共培养是建立T细胞与肿瘤细胞之间相互作用模型的重要途径。但是,有关T细胞与肿瘤细胞共培养方法存在一定难度并缺乏统一性,导致相关研究和应用发展缓慢。该综述主要概述并总结CD4+和CD8+T细胞与肿瘤细胞共培养的方法和应用。
出处 《现代免疫学》 CAS 北大核心 2021年第3期260-264,共5页 Current Immunology
基金 国家自然科学基金地区基金项目(81960869)。
  • 相关文献

参考文献3

二级参考文献46

  • 1Suntaek Hong,Ho-Jae Lee,Seong Jin Kim,Ki-Baik Hahm.Connection between inflammation and carcinogenesis in gastrointestinal tract: Focus on TGF-β signaling[J].World Journal of Gastroenterology,2010,16(17):2080-2093. 被引量:18
  • 2KatherineDCrew,AlfredINeugut.Epidemiology of gastric cancer[J].World Journal of Gastroenterology,2006,12(3):354-362. 被引量:190
  • 3Luvero D, Milani A, Ledermann JA. Treatment options in recurrent ovarian cancer: latest evidence and clinical potential. TherAdv Med Onco12014; 6: 229-239.
  • 4Zsiros E, Tanyi J, Balint K, Kandalaft LE. Immunotherapy for ovarian cancer: recent advances and perspectives. CurrOpin 0ncol2014; 26: 492-500.
  • 5Yigit R, Massuger LF, Figdor CG, Torensma R. Ovarian cancer creates a suppressive microenvironment to escape immune elimination. Gynecol Onco12010; 117: 366-372.
  • 6Facciabene A, Motz GT, Coukos G. T-regulatory cells: key players in tumor immune escape and angiogenesis. Cancer Res 2012; 72: 2162-2171.
  • 7Viehl CT, Moore TT, Liyanage UK, Frey DM, Ehlers JP, Eberlein TJ et al. Depletion of CD4+CD25+ regulatory T cells promotes a tumor- specific immune response in pancreas cancer-bearing mice. Ann Surg 0ncol2006; 13: 1252-1258.
  • 8Liu S, Foulkes WD, Leung S, Gao D, Lau S, Kos Z et al. Prognostic significance of FOXP3+ tumor infiltrating lymphocytes in breast cancer depends on estrogen receptor and human epidermal growth factor receptor-2 expression status and concurrent cytotoxic T-cell infiltration. Breast Cancer Res 2014; 16: 432..
  • 9Salama P, Phillips M, Grieu F, Morris M, Zeps N, Joseph D et al. Tumor-infiltrating FOXP3+ T regulatory cells show strong prognostic significance in colorectal cancer. J Clin Onco12009; 27: 186-192.
  • 10Kiniwa Y, Miyahara Y, Wang HY, Peng W, Peng G, Wheeler TM et al. CD8+ Foxp3+ regulatory T cells mediate immunosuppression in prostate cancer. Clin Cancer Research 2007; 13: 6947-6958.

共引文献34

同被引文献10

引证文献1

二级引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部