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The RIP3-RIP1-NF-κB signaling axis is dispensable for necroptotic cells to elicit cross-priming of CD8^(+) T cells 被引量:1

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摘要 Apoptosis and necroptosis are two types of programmed cell death with distinct morphological features.Necroptosis has been assumed to be more inflammatory than apoptosis,but a recent paper1 concluded that necroptotic cells cannot elicit cross-priming of CD8^(+)T cells and that NF-κB activation in necroptotic cells is required for maximal CD8^(+)T-cell cross-priming.
出处 《Cellular & Molecular Immunology》 SCIE CAS CSCD 2017年第7期639-642,共4页 中国免疫学杂志(英文版)
基金 supported by the National Natural Science Foundation of China(91029304,31420103910,31330047 and 81630042) the National Basic Research Program of China(973 Program,2015CB553800,2013CB944903 and 2014CB541804) the 111 Project(B12001) the National Science Foundation of China for Fostering Talents in Basic Research(J1310027).
关键词 RIP3 PRIMING elicit
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