冠脉痉挛及其诊治的研究进展

Research progress in the diagnosis and treatment of coronary artery spasm

冠脉痉挛患者的胸痛症状与冠脉阻塞性心脏病相似,发作时心电图上有ST-T改变,心脏彩超检查可见室壁运动障碍,并可能出现血清肌钙蛋白水平升高。但冠脉痉挛的病理生理学机制以平滑肌收缩功能障碍为主,与冠脉阻塞性心脏病完全不同,因此两病的治疗原则也完全不同。

The chest pain symptoms in patient with coronary artery spasm are similar to coronary obstructive heart disease.There are ST-T changes in the ECG during the attack,and ventricular wall motion abnormality may occur in the cardiac ultrasound,and the serum troponin level may be elevated.However,the pathophysiological mechanism of coronary artery spasm is mainly smooth muscle contraction dysfunction,which is completely different from coronary obstructive heart disease,so the treatment principles of the two diseases are also completely different.