脓毒症与相关生物分子关系的研究

Study on the Relationship Between Sepsis and Related Biomolecules

脓毒症是由感染引起的全身炎症反应综合征,身体任何部分感染都有可能引发此病,其发病率、死亡率极高。据统计,目前全球每年约有超过1900万脓毒症患者,大部分由严重感染引起,已成为威胁人类生命健康和安全的重大疾病之一。目前,关于脓毒症发生发展的机制研究已进入分子水平,本文主要就相关生物分子在脓毒症的诊断、治疗及预后评估等方面的作用进行综述,以期为临床治疗脓毒症提供指导方向。

Sepsis is a systemic inflammatory response syndrome caused by infection.Infection of any part of the body may cause this disease,and its morbidity and mortality are extremely high.According to statistics,there are currently more than 19 million sepsis patients in the world each year,most of which are caused by serious infections,and have become one of the major diseases that threaten human life,health and safety.At present,research on the mechanism of the occurrence and development of sepsis has entered the molecular level.This article mainly reviews the role of related biomolecules in the diagnosis,treatment and prognosis evaluation of sepsis,in order to provide guidance for the clinical treatment of sepsis.