亲水表面改性的种植体不同时相的骨结合情况和组织学观察

Osseointegration and histological observation of chemically modified implants in different phases

目的观察亲水表面改性处理口腔种植体的骨结合效果。方法4只比格犬,随机分为2周、4周、8周和12周组,于每组犬拔牙2个月后的下颌骨中植入4颗亲水表面改性处理的口腔种植体,按照相应时点取材,测量种植体稳定系数(Implant stability factor,ISQ)、临界旋出扭矩(Critical spin out torque,CST)、骨结合率,并观察不同时点骨结合的状态和组织学特点。结果种植体植入后4周与2周相比,ISQ、CST、骨结合率均显著升高;8W与4W相比,CST、骨结合率均显著升高;12W与8W相比,骨结合率显著升高。结论亲水表面改性处理能够促进种植体骨结合。

Objective To observe the osseointegration effect of hydrophilic surface modified dental implants.Methods four beagle dogs were randomly divided into 2week,4week,8week and 12 week groups.Four hydrophilic surface modified dental implants were implanted into the mandible of 2 months after tooth extraction in each group.Results the ISQ,critical rotation torque and osseointegration rate were significantly increased at 4 weeks compared with 2 weeks;the critical rotation torque and osseointegration rate were significantly increased at 8 weeks compared with 4 weeks;the osseointegration rate was significantly increased at 12 weeks compared with 8 weeks.Conclusion Hydrophilic surface modified surface treatment promotes osseointegration of implants.