运动干预对胃癌化疗患者癌因性疲乏及睡眠质量的影响

Effects of exercise intervention on cancer-induced fatigue and sleep quality in patients with gastric cancer undergoing chemotherapy

目的:探讨有氧结合抗阻运动在胃癌化疗患者中癌因性疲乏及睡眠质量的效果。方法:将126例胃癌化疗患者随机分成对照组和观察组,每组各63例。对照组接受常规护理,观察组在此基础上实施8周的运动干预措施。采用Piper疲乏修正量表(Revised piper fatigue scale,RPFS)、匹兹堡睡眠质量指数(Pittsburgh sleep quality index,PSQI)评估患者干预前(首次化疗前1天)、干预8周后的疲乏程度及睡眠质量。结果:两组患者干预前疲乏程度得分、睡眠质量得分差异均无统计学意义(P>0.05)。干预后,观察组的睡眠质量得分、疲乏程度得分均低于对照组,差异有统计学意义(P<0.05)。结论:运动干预可显著降低癌因性疲乏的发生率,同时改善患者的睡眠质量。

Objective To investigate the effect of aerobic exercise combined with resistance exercise on cancer-induced fatigue,sleep quality in patients with gastric cancer undergoing chemotherapy.Method 126 patients with gastric cancer treated with chemotherapy were randomly divided into control group and observation group,with 63 patients in each group.The control group was received routine nursing care,and the observation group was implemented the exercise intervention measures for 8 weeks on this basis.Patients were evaluated with the Piper Piper fatigue scale(RPFS),the Pittsburgh sleep quality index(PSQI)before intervention(1 day before chemotherapy),and their fatigue and sleep quality after 8 weeks of intervention.Results The score of fatigue before intervention and the difference of sleep quality between the two groups were not statistically significant(P>0.05).After intervention,the score of sleep quality and the score of fatigue degree in the observation group were lower than that in the control group(P<0.05).Conclusion Exercise intervention can significantly reduce the incidence of cancer-related fatigue and improve the sleep quality of patients.