芍药甘草汤化学成分及药理作用研究进展

Research progress on chemical constituents and pharmacological activities of Shaoyao Gancao Decoction

芍药甘草汤由白芍、炙甘草两味中药组成,具有调和肝脾、柔筋止痛等功效,是中医临床常用的缓急止痛之方。文献报道芍药甘草汤主要含有黄酮类、三萜皂苷类、单萜糖苷类、酚酸类、鞣质类、生物碱类、糖类等化学成分;药理研究表明芍药甘草汤具有解痉镇痛、保肝、抗炎、止咳、平喘、抗变态反应等药理作用。就近年来国内外对芍药甘草汤化学成分及药理作用的研究结果进行论述,为进一步综合开发利用奠定基础。

Shaoyao Gancao Decoction, which is composed of paeonia lactiflora and honey-fried licorice root, has the functions of reconciling liver and spleen, soothing tendon and relieving pain. It is a commonly used prescription for relieving pain in traditional Chinese medicine. Literature reports that Shaoyao Gancao Decoction mainly contains flavonoids, triterpene glycosides, monoterpene glycosides, phenolic acids, tannins, alkaloids, saccharides and other chemical constituents. It has the pharmacological effects of antispasmodic and analgesic, liver protection, anti-inflammatory, anti-cough, anti-asthmatic, anti-allergic activities and so on. In this paper, the chemicals and pharmacological activities of Shaoyao Gancao Decoction were summarized to lay a foundation for further research.