摘要
帕金森病(Parkinson's disease,PD)是神经退行性疾病中的一种,以中老年人发病多见,主要临床表现以运动症状为主。近年来非运动症状在帕金森病的相关研究中越来越多见,其中嗅觉障碍为帕金森病非运动症状中极为重要的一种,与帕金森病关系密切,可早于运动症状出现,甚至成为首发症状。针对PD嗅觉障碍的诊断方法、发病机制、相关因素及治疗的研究进展进行综述具有现实意义。
Parkinson's disease(PD)is one of the neurodegenerative diseases,mainly occuring in middle-aged and elderly people,and its main clinical manifestations are motor symptoms.In recent years,non-motor symptoms have become more and more common in the related studies of Parkinson's disease.Among them,dysosmia is one of the most important non-motor symptoms of Parkinson's disease,which is closely related to Parkinson's disease.It can appear earlier than motor symptoms and even become the first symptom.This article reviews the research progress of the diagnosis,pathogenesis,related factors and treatment of PD olfactory disorder,and has practical significance.
作者
王一帆
简崇东
WANG Yifan;JAN Chongdong(Neurology Department of Affiltiated Hospital,,Youjiang Medical Uniersity for Natioraliries,Brise 533000,Guangxi,China;Graduate School,Youjiang Medical Uniersity for Natioraliries,Brise 533000,Guangxi,China)
出处
《右江医学》
2021年第6期401-404,共4页
Chinese Youjiang Medical Journal
基金
国家自然科学基金(81860244)
广西自然科学基金(2018GXNSFAA281051,2020GXNSFAA259057)
右江民族医学院附属医院第一批高层次人才科研项目(R20196308)。
关键词
帕金森病
嗅觉障碍
检测方法
发病机制
相关因素
治疗
Parkinson's disease
olfactory disorder
detection method
pathogenesis
correlative factors
treatment
