摘要
One rare tetracyclic macroline-type indole alkaloid,named rauvoyunine A(1),and two new picraline-type alkaloids rauvoyunines B and C(2 and 3)were isolated from the aerial parts of Rauvolfia yunnanensis.Their structures were elucidated on the basis of extensive spectroscopic analysis.Compounds 2 and 3 were evaluated for their in vitro cytotoxicity against five human tumor cell lines.
基金
This work was financially supported by National Basic Research Program of China(973 Program)2009CB522300
the“West Light”program of Chinese Academy of Sciences,and Natural Product Library Program of BioBioPha.