摘要
New hexalobine type alkaloid,5-(200,300-epoxy-300-methylbutyl)-3-(30-hydroxy-30-methyl-10-acetyloxy-but-20-yl)indole(1)alongside the known hexalobines 3-(20,30-dihydroxy-30-methylbutyl)-5-(300-methylcrotonoyl)indole(2),3,5-hexalobine C(3)and 3,5-hexalobine D(4)were isolated from fruits of Hexalobus monopetalus.Compounds 3 and 4 exhibited antifungal activity against Candida albicans.
基金
The Norwegian Agency for International Development(NORAD)through the NORAD Chemistry Project is appreciated for supporting this work through a scholarship grant to H.M.M
The National Institute for Medical Research(NIMR),The Department of Chemistry at the University of Dar es Salaam in Tanzania
the Department of Pharmaceutical Chemistry in the Institute of Pharmacy at Erlangen University in Germany are thanked for supporting the research project.