摘要
Six new indole alkaloids,named alstoniascholarines L–Q(1–6),together with nineteen known analogues were isolated from the inadequately dried leaves of Alstonia scholaris.Their structures were elucidated on the basis of extensive analysis of spectroscopic data and by comparison of their physical and spectroscopic data with the literature values.In addition,the new alkaloids were tested for their cytotoxic and neurite outgrowth-promoting activities.
基金
The authors are grateful to the Natural Science Foundation of China(81225024)
Collaborative Innovation Center of Southwest EthnicMedicine(Guangxi Normal University),(CICSEM 2013-A)
the Ministry of Science and Technology of the People’s Republic of China(2014ZX09301307-003)
the Chinese Academy of Sciences(KSZD-EW-Z-004-03)for partial financial support。