摘要
Cellular reprogramming to neural cells is an area of ongoing study in developmental neuroscience,and recent research has generated remarkable achieve-ments.Several studies have shown that the ectopic expression of specific neural transcription factors can convert terminally differentiated cells into neural cells.Here,we review the most recent progress in the field of induced neuronal(iN)cells and induced neural stem(iNS)cells and their potential clinical applications.
基金
supported by the National Basic Research Program(973 Program)(No.2011CBA00402,J.J.)
the“Strategic Priority Research Program”of the Chinese Academy of Sciences(No.XDA01020301,J.J.)
the Hundred Talent Program(J.J.).
