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Higher-order genomic organization in pluripotent stem cells

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摘要 Recent applications of new tools for genome-wide mapping of long-range and spatial interactions have shed light onto the fundamental mechanisms of three dimensional chromatin organizations in pluripotent stem cells and their derivatives.Pluripotent stem cells(PSCs),including embryonic stem cells(ESCs)and induced pluripotent stem cells(iPSCs),can pro-liferate limitlessly and differentiate into many types of somatic cells in vitro,providing great promise for basic research and clinical therapy.
出处 《Protein & Cell》 SCIE CSCD 2012年第7期483-486,共4页 蛋白质与细胞(英文版)
基金 G.-H.L.was supported by the National Laboratory of Biomacro-molecules,the 100 Talents Program of Chinese Academy of Sci-ences,a CIRM grant(No.TG2-01158) a Glenn Foundation grant.J.Q.was supported by the AFAR/Ellison Medical Foundation.
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