血小板源性生长因子预测恶性肿瘤患者经外周中心静脉置管后血栓形成的临床价值

Clinical value of platelet-derived growth factor in predicting thrombosis after peripherally inserted central venous catheter in patients with malignant tumors

研究血清中血小板源性生长因子(PDGF)预测恶性肿瘤患者经外周中心静脉置管(PICC)后血栓形成的临床价值。将行PICC、符合纳入标准的526例恶性肿瘤患者根据PICC后10~15 d内是否发生血栓分为血栓组和无血栓组,比较2组患者血清中PDGF等指标的变化。结果发现,PICC后血栓组患者血清中PDGF含量明显高于无血栓组患者,且明显高于PICC前,提示PDGF含量增高可能与血栓形成有关。