摘要
目的系统评价运动干预对系统性红斑狼疮(systemic lupus erythematosus,SLE)患者疲乏的改善效果。方法计算机检索PubMed、Web of science、Embase、CINAHL、Cochrane Library、中国知网数据库、万方数据库、维普中文期刊数据库和中国生物医学文献数据库,纳入自建库起至2020年3月关于运动干预对SLE患者疲乏效果的试验研究。由2名研究员独立进行文献筛选、资料提取,并对文献进行偏倚风险评估。采用RevMan 5.3软件进行Meta分析。结果最终纳入8项研究,其中5项研究进入Meta分析,共343例患者。结果显示,≥12周的运动干预对SLE患者疲乏改善有显著意义[SMD=-0.62,95%CI(-0.85,-0.39),P<0.001]。5项研究为每次至少30 min、每周至少3次的中等强度有氧运动,运动不良事件发生率和样本流失率较高。结论持续时间≥12周的有氧运动有助改善SLE患者疲乏症状;未来研究建议进一步规范干预方案策略,以促进运动安全性和依从性。
Objective To systematically evaluate the effects of exercise on improving fatigue of patients with systemic lupus erythematosus(SLE).Methods Database of PubMed,Web of Science,Embase,CINAHL,Cochrane Library,CNKI,Wanfang,VIP and CBM were searched for clinical trials related to the effects of exercise on improving fatigue in SLE patients,which were published from the establishment to March,2020.Two researchers independently screened studies,extracted data and assessed risk of bias.Meta-analysis was performed by RevMan 5.3 software.Results A total of eight studies were included,and 5 studies were included in Meta-analysis,involving 343 SLE patients.The results showed that exercise greater than or equal to 12 weeks could improve the fatigue of patients with SLE[SMD=-0.62,95%CI(-0.85,-0.39),P<0.001].Most studies were aerobic exercise of at least 30 minutes at a time and 3 times a week.The safety and adherence were high.Conclusions Aerobic exercise lasted more than 12 weeks has a positive effect on improving fatigue in SLE patients.It is suggested that the intervention strategy should be further standardized in the future to promote the safety and compliance of sports.
作者
袁书琪
王会儒
钱丽萍
李挺
沈怿雯
袁晓玲
YUAN Shuqi;WANG Huiru;QIAN Liping;LI Ting;SHEN Yiwen;YUAN Xiaoling(School of Nursing,Shanghai Jiaotong University,Shanghai 200025,China;Department of Physical Education,Shanghai Jiaotong University;Department of Nursing,Lujiazui Community Healthcare Center,Pudong New Area,Shanghai 200120,China;Department of Rheumatology,Renji Hospital Affiliated to Medical College of Shanghai Jiaotong University,Shanghai 201112,China)
出处
《解放军护理杂志》
CSCD
北大核心
2021年第7期20-24,共5页
Nursing Journal of Chinese People's Liberation Army
基金
上海交通大学护理学院本科毕业设计基金(HLBKBSJJ20-05)
国家社会科学基金项目(18BTY097)。