摘要
为了满足实际应用对低成本、易制备表面增强拉曼散射(SERS)基底的需求,采用等离子体技术处理聚甲基丙烯酸甲酯(PMMA)材料层,在其表面形成纳米纤维森林结构,结合金属溅射工艺,制备SERS基底。在理论分析PMMA纳米纤维的形成机理的基础上,以罗丹明6G(R6G)作为探针分子,进行基底的SERS性能测试。结果表明,该SERS基底的检测限达到10-10 mol/L,增强因子达到1.75×10^(6),相对标准偏差为6.52%,且在30 d内可以保持较好的稳定性,在生化检测领域具有很大的实际应用潜力。
To meet the needs of low-cost and easy-to-prepare surface enhanced Raman scattering(SERS)substrate in practical application,plasma technology was used to treat poly(methyl methacrylate)(PMMA)to form nanofiber structures on the surface,and combined with metal sputtering process,to prepare SERS substrate.On the basis of the theoretical analysis of the formation mechanism of PMMA nanofibers,rhodamine 6G(R6G)was used as the probe molecule to investigate the SERS performance of the substrate.The results show that the limit of detection of the SERS substrate is 10-10 mol/L,the enhancement factor is 1.75×10^(6),and the relative standard deviation is 6.52%.Moreover,the SERS subsrtate can maintain good stability within 30 days,illustrating a great potential for practical application in the field of biochemical detection.
作者
李锐锐
杨帅
毛海央
陈大鹏
熊继军
LI Ruirui;YANG Shuai;MAO Haiyang;CHEN Dapeng;XIONG Jijun(Science and Technology on Electronic Test and Measurement Laboratory,North University of China,Taiyuan 030051,China;Key Laboratory of Instrumentation Science and Dynamic Measurement,Ministry of Education,North University of China,Taiyuan 030051,China;Integrated Circuit Pilot Process R&D Center,Institute of Microelectronics of Chinese Academy of Sciences,Beijing 100029,China)
出处
《太原理工大学学报》
CAS
北大核心
2021年第4期585-591,共7页
Journal of Taiyuan University of Technology
基金
国家自然科学基金资助项目(61771467,51935011)
中国科学院青年创新促进会资助项目(2018153)
广东省重点领域研发计划资助项目(2019B010117001)
山西省“1331”项目“重点学科建设”资助项目。
关键词
等离子体技术
聚甲基丙烯酸甲酯
表面增强拉曼散射
生化检测
plasma technology
poly(methyl methacrylate)
surface enhanced Raman scattering
biochemical detection
