CHA_(2)DS_(2)-VASc评分对心源性短暂性脑缺血发作鉴别诊断价值的研究

Value of CHA_(2)DS_(2)-VASc score in the differential diagnosis of cardioembolic transient ischemic attack

目的探讨CHA_(2)DS_(2)-VASc评分及ABCD2评分对心源性短暂性脑缺血发作(TIA)的鉴别诊断价值。方法回顾经临床诊断为心源性TIA和非心源性TIA的60例患者的临床资料及ABCD2、CHA_(2)DS_(2)-VASc评分结果,进行对比分析。结果两组性别、年龄、伴发病及持续时间、临床症状、既往卒中病史等基线特征未发现明显差异,CHA_(2)DS_(2)-VASc评分有显著差异(t=2.70,P<0.05),CHA_(2)DS_(2)-VASc评分诊断心源性TIA ROC曲线下面积为0.682(95%CI0.526~0.837,P<0.05)。结论CHA_(2)DS_(2)-VASc评分在临床TIA的实际管理中能够作为参考指标帮助鉴别心源性TIA的可能,从而指导及早院内干预。

Objective To explore CHA_(2)DS_(2)-VASc score and ABCD2 score values in differential diagnosis of cardiogenic transient ischemic attack(TIA).Methods Clinical data and ABCD2,CHA_(2)DS_(2)-VASC score results of 60 patients with clinically confirmed cardiogenic TIA(group A)and non-cardiogenic TIA(group B)were reviewed and compared.Results There were no significant differences in baseline characteristics between the two groups,such as gender,age,associated onset and duration,clinical symptoms,and previous history of stroke,but there were significant differences in CHA_(2)DS_(2)-VASc scores(t=2.70,P<0.05),and the area under the ROC curve of the CHA_(2)DS_(2)-VASC score for the diagnosis of cardiogenic TIA was 0.682(95%CI:0.526-0.837,P<0.05).Conclusion CHA_(2)DS_(2)-VASC score can be used as a reference index in the actual management of clinical TIA to help identify the possibility of cardiogenic TIA,so as to guide early intervention in hospitals.