摘要
目的建立达原饮胃漂浮片处方药材提取工艺。方法以芍药苷、黄芩苷、汉黄芩苷、黄芩素、芒果苷和新芒果苷含量为评价指标,采用正交试验法筛选最佳提取工艺。结果通过正交试验和验证试验,达原饮胃漂浮片的最佳提取工艺为A_(2)B_(3)C_(2)D_(2),即85%乙醇,料液比为20倍量,提取时间为1 h,提取2次。结论达原饮胃漂浮片处方药材提取操作简单、工艺可行。
Objective To establish an extraction process of Dayuan Yin gastric floating tablets prescription medicinal materials.Methods Contents of paeoniflorin,baicalin,wogonoside,baicalein,mangiferin and neomangiferin as evaluation indexes,and the orthogonal test is used to screen the best extract process.Results Through orthogonal experiment and verification,the optimal technology for Dayuan Yin gastric floating tablets is A_(2)B_(3)C_(2)D_(2),that is the 85%ethanol,the material-liquid ratio is 20 times,the number of extraction is 2 times,and the extraction time is 1 h.Conclusion The extraction technology for Dayuan Yin gastric floating tablets is simple and feasible.
作者
申茹
徐英辉
郭玉岩
麦艳珍
余巧
毛一中
SHEN Ru;XU Ying-hui;GUO Yu-yan;MAI Yan-zhen;YU Qiao;MAO Yi-zhong(Department of Pharmacy,Huizhou Health Sciences Polytechnic,Huizhou 516025,China;Huizhou Key Laboratory of Medicinal Plant Research and Development,Huizhou 516025,China;School of Pharmacy,Heilongjiang University of Traditional Chinese Medicine,Harbin 150040,China)
出处
《现代中药研究与实践》
CAS
2021年第3期61-65,共5页
Research and Practice on Chinese Medicines
基金
国家自然科学基金资助项目(81703724)
2020年度惠州市医疗卫生类科技计划项目(2020Y167)
2018年广东省普通高校特色创新项目(2018GKTSCX097)。
关键词
达原饮
胃漂浮片
HPLC
提取工艺
Dayuan Yin
gastric floating tablets
HPLC
extraction process