珠海市男男性行为者HIV抗体重复检测影响因素

Influencing factors of repeat HIV testing among men who have sex with men in Zhuhai

目的分析珠海市男男性行为者(MSM)HIV抗体重复检测的特征及影响因素,为促进MSM群体HIV定期检测提供参考依据。方法2018年6月至2019年5月,社会组织以互联网+社交媒体为平台,采用HIV自我检测模式和基于医疗点的HIV快速检测模式招募MSM,收集其人口学和性行为特征等信息,开展HIV-梅毒抗体检测,并在自然队列中观察人群的HIV重复检测情况,采用c2检验和非条件多因素Logistic回归模型进行统计学分析。结果共755名MSM纳入分析,重复检测比例为26.9%(203/755)。单因素分析结果显示,文化程度(χ^(2)=9.074,P<0.05)和检测模式(χ^(2)=5.855,P<0.05)与重复检测有关联;多因素Logistic回归分析结果显示,文化程度为大专及以上的MSM更倾向于重复检测(OR=1.56,95%CI:1.112.20)。HIV抗体筛查阳性者的重复检测比例3.28%低于HIV抗体筛查阴性者的29.0%,差异有统计学意义(χ^(2)=18.816,P<0.001)。参与HIV自检的MSM重复检测时间间隔小于参与医疗点HIV快速检测的MSM重复检测时间间隔,时间间隔中位数为28(9,56)d vs.94(54,133)d,差异有统计学意义(Z=-9.357,P<0.001)。结论珠海市MSM群体HIV抗体重复检测比例较低,应重点提高低文化程度MSM的HIV感染风险意识和检测意识,鼓励MSM采用HIV自检模式定期监测自身感染状况。

Objective To analyze the characteristics of repeat HIV testing among men who have sex with men(MSM),and provide evidence for promoting repeat HIV testing and increasing testing frequency.Methods MSM who participating in internet-based HIV self-testing and clinics-based HIV rapid diagnostics testing,were recruited in Zhuhai city by Zhuhai MSM social organization from June 2018 to May 2019.Data on demographic and sexual behavioral characteristic and the results of testing for HIV and syphilis were collected.The number of repeated tests in the study period were recorded.Data were analyzed by the Chi-squared test and non-conditional Logistic regression.Results A total of 755 MSM were included in this study and 203 of them had repeat HIV tests(26.9%).The results of univariate analysis showed that the education level(χ^(2)=9.074,P<0.05)and the test method(χ^(2)=5.855,P<0.05)were correlated with the repeat HIV testing.Multivariate Logistic regression analysis showed that participants with college and above education level were more willing to repeat the test(OR=1.56,95%CI:1.11-2.20).The repeat test rate of HIV antibody screening positive group was 3.28%,which was lower than 29.0%of HIV antibody screening negative group(χ^(2)=18.816,P<0.001).The time interval between repeat tests for MSM participating in HIV self-testing was shorter than that for MSM participating in rapid HIV testing at health care points,with a median interval of 28(9,56)days vs.94(54,133)days(Z=-9.357,P<0.001).Conclusion MSM in Zhuhai city had a low proportion of repeat HIV testing.It should be necessary to increase the publicity and promotion of repeat HIV testing,raise the awareness of HIV risk,and encourage MSM to use HIV self-testing as routine testing tool to monitor their own infection status.