摘要
鼻-眼-脑型毛霉菌感染病情凶险,进展迅速,早发现、早诊断是提高治愈率的关键。泊沙康唑联合两性霉素B脂质体鞘内注射成功治疗脑毛霉菌病报道较少。本文对某院1例使用泊沙康唑联合静脉滴注、鞘内注射两性霉素B脂质体成功治疗急性淋巴细胞白血病合并鼻-眼-脑型毛霉菌病的病例进行报告及文献复习。
Rhino-orbital-cerebral mucormycosis is an extremely dangerous disease with rapid progress,early detection and early diagnosis is the key to improve the cure rate.There are few reports on successful treatment for cerebral mucormycosis through intrathecal injection of posaconazole combined with amphotericin B liposome.In this article,successful treatment of one case of rhino-orbital-cerebral mucormycosis through posaconazole combined with intravenous drip and intrathecal injection of amphotericin B liposome in a hospital is reported and related literatures are reviewed.
作者
高陆
彭志元
冯永怀
袁钟
GAO Lu;PENG Zhi-yuan;FENG Yong-huai;YUAN Zhong(Department of Hematology,Affiliated Hospital of Zunyi Medical University,Zunyi 563000,China)
出处
《中国感染控制杂志》
CAS
CSCD
北大核心
2021年第7期663-667,共5页
Chinese Journal of Infection Control
基金
遵义医科大学硕士启动基金[院字(2018)27号]。
关键词
鼻-眼-脑型毛霉菌病
泊沙康唑
两性霉素B脂质体
鞘内注射
手术清创
rhino-orbital-cerebral mucormycosis
posaconazole
amphotericin B liposome
intrathecal injection
surgical debridement