重症肺炎合并脓毒症患者的临床特征分析

Clinical analysis of patients with severe pneumonia complicated with sepsis

目的:分析重症肺炎合并脓毒症患者的临床特点。方法:收集2014年1月-2019年12月期间我院急诊科收治的重症肺炎合并脓毒症患者101例。根据预后分为存活组(38例)与死亡组(63例),回顾性分析比较两组的临床资料。结果:死亡组呼吸频率、心率、血肌酐值及尿素氮值、PSI评分及应用有创机械通气的比例高于存活组,住院天数、血红蛋白及白蛋白值低于存活组,差异有统计学意义(P<0.05),多因素Logistic回归分析显示PSI评分、呼吸频率、住院天数及有创辅助通气是重症肺炎合并脓毒症患者预后的独立危险因素。结论:PSI评分、呼吸频率及有创辅助通气是重症肺炎合并脓毒症患者预后的独立危险因素。

Objective:To analyze clinical characteristics of severe pneumonia complicated with sepsis.Methods:A total of 101 patients with severe pneumonia complicated with sepsis admitted to our hospital from January 2014 to December 2019 were collected.According to the prognosis,they were divided into survival group(38 cases)and death group(63 cases),and the clinical data between the two groups were retrospectively analyzed.Results:The breathing rate,heart rate,serum creatinine and urea nitrogen values,PSI score and application of invasive mechanical ventilation ratio were higher in death group,while days of hospital stay,hemoglobin and albumin value were lower than those in the survival group,with statistically significant differences.The Multivariate Logistic regression analysis showed that the PSI score,breathing rate,days of hospital stay and invasive ventilation were independent risk factors of death in patients of severe pneumonia with sepsis.Conclusion:PSI score,respiratory rate and invasive mechanical ventilation were independent risk factors for the prognosis of patients with severe pneumonia complicated with sepsis.