上尿路尿路上皮癌治疗方式的选择

Selection of treatment for upper tract urothelial carcinoma

上尿路尿路上皮癌是指发生于上尿路(肾盂或输尿管)的尿路上皮恶性肿瘤,目前外科治疗的金标准仍是根治性肾输尿管切除术联合膀胱袖状切除。但对于某些患者,如孤立肾、双侧肿瘤及肾功能不全的患者,在充分评估后也可实行保留肾脏的手术方式。无论是哪一种手术方式,术后局部药物灌注治疗都有一定的辅助疗效。但对于较为晚期的转移性患者,姑息性治疗则是不可避免的。

Upper tract urothelial carcinoma is a malignant urothelial neoplasm occurring in the upper urinary tract(renal pelvis or ureter).At present,the gold standard of surgical treatment is still radical nephroureterectomy combined with bladder cuff excision.However,for some patients,who have isolated kidneys,bilateral tumors or renal insufficiency,kidney-sparing surgery can also be performed after adequate evaluation.No matter what kind of operation,postoperative local drug infusion therapy has a certain auxiliary effect.However,palliative treatment is inevitable for patients with advanced metastatic disease.