温通散熏洗辅治糖尿病合并周围神经病变疗效观察

Observation on the Curative Effect of Wentong Powder Fumigation and Washing in the Adjuvant Treatment of Diabetes with Peripheral Neuropathy

目的:观察温通散熏洗辅治糖尿病合并周围神经病变的疗效。方法:96例随机分为治疗组和对照组各48例。两组均给予甲钴胺片,治疗组加用温通散熏洗。结果:两组治疗后空腹血糖、糖化血红蛋白均较治疗前降低(P<0.05),但组间比较差异无统计学意义(P>0.05)。临床总有效率治疗组高于对照组(P<0.05)。治疗后两组Toronto评分均较治疗前降低(P<0.05),治疗组低于对照组(P<0.05);两组腓总神经和胫神经的SNCV、MNCV均加快(P<0.05),且治疗组快于对照组(P<0.05)。两组胫前、胫后、足背动脉流速均加快(P<0.05),且治疗组快于对照组(P<0.05)。两组不良反应发生率差异无统计学意义(P>0.05)。结论:温通散熏洗辅治糖尿病合并周围神经病变可改善临床症状,提高治疗有效率,且不良反应小。

Objective:To observe the curative effect of Wentong Powder with fumigation and washing as an auxiliary treatment of diabetes with peripheral neuropathy.Methods:Ninety-six cases were randomly divided into treatment group and control group,with 48 cases in each group.Both groups were given mecobalamin tablets,and the treatment group was fumigated and washed with Wentong Powder in addition.Results:The fasting blood glucose and glycosylated hemoglobin were lower in the two groups after treatment than those before treatment(P<0.05),but there was no significant difference between the groups(P>0.05).The total clinical effective rate of the treatment group was higher than that of the control group(P<0.05).The Toronto scores of the two groups were lower after treatment than those before treatment(P<0.05),and the treatment group was lower than that of the control group(P<0.05).The SNCV and MNCV of the common peroneal nerve and tibial nerve in both groups were accelerated(P<0.05),and those of the treatment group were faster than those of the control group(P<0.05).The flow velocity of the anterior tibial,posterior tibial and dorsal foot arteries in the two groups were accelerated(P<0.05),and those of the treatment group were faster than those of the control group(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:Wentong Powder with fumigation and washing as an auxiliary treatment of diabetes with peripheral neuropathy can improve the clinical symptoms,increase the effective rate of treatment,with small adverse reactions.