健康脊髓及脊髓疾病DTI量化研究进展

Research progress of DTI quantification in myelopathy

目前,脊髓磁共振成像存在诸多局限性,近年来随着扩散张量成像(diffusion tensor imaging,DTI)应用,改善了脊髓成像质量,使定量测量成为可能,并逐渐应用于各种脊髓疾病诊断。作者对脊髓DTI成像技术及在健康脊髓、肌萎缩侧索硬化症(amyotrophic lateral sclerosis,ALS)、脊髓压迫症、脊髓炎、多发性硬化(multiple sclerosis,MS)、脊髓损伤(spinal cord injury,SCI)和肿瘤等多种脊髓疾病中的应用进行了综述。脊髓DTI成像除能定量描述健康脊髓的扩散特点,还能早期诊断各种脊髓疾病并明确病变范围,监测病情进展及评估术后恢复情况。

At present,there are many limitations in spinal magnetic resonance imaging.In recent years,with the application of diffusion tensor imaging(DTI),the quality of spinal imaging has been improved,and quantitative measurement has become possible,and it has been gradually applied in the diagnosis of various spinal diseases.In this paper,DTI imaging of spinal cord was studied in healthy spinal cord,amyotrophic lateral sclerosis(ALS),spinal cord compression,myelitis,multiple sclerosis.The applications of spinal cord injury(SCI),spinal cord injury(MS)and tumor were reviewed.DTI imaging of spinal cord can not only quantitatively describe the diffuse characteristics of healthy spinal cord,but also early diagnose various spinal cord diseases and define the lesion range,monitor the progress of the disease and evaluate the postoperative recovery.