伴眩晕与不伴眩晕突发性聋临床特点及血脂对比分析

A comparative analysis of clinical characteristics and blood lipids of sudden deafness with and without vertigo

目的分析伴眩晕突发性聋与不伴眩晕突发性聋患者临床资料及血脂检查,总结其发病特点、加深对该疾病认识。方法回顾性分析南充市中心医院耳鼻喉头颈外科136例突发性聋患者的发病特点、听力检查、血脂检查、疗效等资料,根据其病程中有无眩晕将其分为突发性聋伴眩晕组(sudden deafness and vertigo,SDV)与突发性聋不伴眩晕组(sudden deafness without vertigo,SDwV),分析发病性别、年龄构成比、听力损失程度、住院日、血胆固醇、甘油三酯、高密度脂蛋白、低密度脂蛋白、伴发良性阵发性位置性眩晕(benign paroxysmal positional vertigo,BPPV)及疗效。以SAS 8.0软件进行统计分析。结果SDV组30例,SDwV组106例。两组间年龄、性别、发病至入院时间、住院治疗时间、伴耳鸣、血总胆固醇、甘油三酯、高密度脂蛋白、低密度脂蛋白均无统计学差异(P>0.05)。患者中伴BPPV 7例,经复位治疗后眩晕症状消失。SDV组与SDwV组间听力损失程度差异有统计学意义(P<0.05),SDV组听力损失程度更重。SDV组和SDwV组间治疗有效率、显效率差异均无统计学差异(P>0.05)。但SDwV组痊愈率为15.1%,SDV组痊愈率为0,两组间差异有统计学意义(P<0.05)。结论突发性聋伴眩晕相较于不伴眩晕者,听力损失程度更重、痊愈率更低。突发性聋伴发的眩晕部分为BPPV,手法复位后眩晕恢复较好。暂未发现年龄、性别、伴耳鸣及血脂与突发性聋是否伴眩晕的关系。

Objective To analyze the clinical data and blood lipid examination of the patients with sudden deafness which with and without vertigo,summarize the characteristics of the disease and deepen the understanding of the disease.Methods A retrospective analysis of 136 cases of sudden deafness in otolaryngology head and neck surgery of Nanchong central hospital was carried out.The data were divided into two groups:sudden deafness and vertigo(SDV);sudden deafness without vertigo(SDwV),to analyze the sex,age composition,hearing loss,length of stay,blood cholesterol,triglyceride,high-density lipoprotein,low-density lipoprotein,benign paroxysmal positional vertigo and its curative effect.SAS 8.0 software was used for statistical analysis.Results There were 30 cases in the SDV group and 106 cases in the SDwV group.There were no significant differences between the two groups in age,gender,time from onset to admission,time of hospitalization,tinnitus,total cholesterol,triglyceride,high-density lipoprotein and low-density lipoprotein(P>0.05).BPPV was found in 7 patients and vertigo disappeared after reduction.The difference of hearing loss between SDV group and SDwV group was statistically significant(P<0.05).There was no significant difference between SDV group and SDwV group(P>0.05).However,the recovery rate of SDwV group was 15.1%,and the recovery rate of SDV group was 0,the difference between the two groups was statistically significant(P<0.05).Conclusion Compared with those without vertigo,sudden deafness with vertigo has more severe hearing loss and lower recovery rate.BPPV is the vertigo part of sudden deafness,and the vertigo recovery is better after manual reduction.No relationship between age,gender,tinnitus,blood lipid and vertigo was found.