NCPAP用于阻塞性睡眠呼吸暂停低通气综合征的临床效果研究

Study on the clinical effect of NCPAP in obstructive sleep apnea hypopnea syndrome

目的探究阻塞性睡眠呼吸暂停低通气综合征(OSAHS)应用持续气道正压通气(NCPAP)治疗的临床疗效。方法选择本院2018年10月至2020年7月期间收治的46例OSAHS患者,按照随机数字表法分为两组,其中开展常规保守治疗的23例患者为对照组,在此基础上应用NCPAP治疗的23例患者为观察组,观察两组患者治疗前后AOPP水平、MMSE评分及多导睡眠监测指标。结果治疗后观察组AOPP水平低于对照组,MMSE评分高于对照组(P<0.05)。治疗后观察组LSaO2高于对照组,LAT、RDI、AI、HI均低于对照组(P<0.05)。结论OSAHS应用NCPAP治疗可降低机体氧化应激反应,改善患者认知功能障碍及通气功能,提高患者睡眠质量。

Objective To explore the clinical efficacy of continuous positive airway pressure(NCPAP)in the treatment of obstructive sleep apnea hypopnea syndrome(OSAHS).Methods 46 patients with OSAHS who were admitted to our hospital from October 2018 to July 2020 were selected and divided into two groups according to the random number table method.Among them,23 patients who were treated with conventional conservative treatment were the control group.and 23 patients treated with NCPAP on this basis were selected as the observation group.Observe the AOPP level,MMSE score and polysomnography monitoring index of the two groups of patients before and after treatment.Results After treatment,the AOPP level of the observation group was lower than that of the control group,and the MMSE score was higher than that of the control group(P<0.05).After treatment,LSaO2 in the observation group was higher than that in the control group,and LAT,RDI,AI and HI were lower than those in the control group(P<0.05).Conclusion OSAHS application of NCPAP treatment can reduce the body’s oxidative stress response,improve patients’cognitive dysfunction and ventilation function,and improve patients’sleep quality.