影响OSA患者合并焦虑/抑郁情绪多因素临床分析

Clinical analysis about the influencing factors in patients with obstructive sleep apnea combined with anxiety and depression emotion

目的探讨影响OSA患者合并焦虑/抑郁的多种因素。方法收集新疆医科大学第四附属医院呼吸内科收治的OSA患者筛选核心信息、床旁PSG监测、ESS评分、医院焦虑抑郁量表等问卷调查数据,分为合并焦虑\抑郁组和非焦虑、抑郁组,通过回顾性分析,比较2组间不同临床特征的差异,以及各临床特征与受试者HAD的相关性。结果符合纳入标准的OSA患者共185例,其中102例(55.14%)合并焦虑\抑郁,在合并焦虑\抑郁和非焦虑、抑郁组之间差异具有统计学意义(P <0.05),临床参数包括性别、年龄、BMI、ESS、AHI、LSO2及受教育程度与HAD存在相关性。结论 OSA合并焦虑\抑郁情况不容忽视,焦虑\抑郁的发生与BMI、ESS、AHI、LSO2及教育程度密切相关,即OSA程度越重,发生焦虑\抑郁的风险越高。积极控制OSA促进患者身心健康。

Objective To explore the multiple factors affecting OSA patients combined with anxiety/depression. Methods The core screening information, bedside PSG monitoring, ESS score, hospital anxiety and depression scale and other questionnaire data of OSA patients admitted to the department of respiratory medicine of the fourth affiliated hospital of Xinjiang medical university were collected.The patients were divided into two groups, the combined anxiety/depression group and the non-anxiety/depression group. Through retrospective analysis, different clinical characteristics between the two groups were compared, and the correlation between clinical characteristics and HAD of the subjects were studied.Results A total of 185 OSA patients met the inclusion criteria, of which 102 cases(55.14%)were combined with anxiety/depression, and there was a statistically significant difference between the two groups(P < 0.05).Clinical parameters including gender, age, BMI, ESS, AHI, LSO2 and education level were associated with HAD. Conclusion OSA combined with anxiety/depression should not be ignored, the occurrence of anxiety/depression is closely related to BMI, ESS, AHI, LSO2 and education level.The higher the degree of OSA, the higher the risk of developing anxiety/depression is. Active control OSA could promote the physical and mental health of patients.